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To evaluate the optimal scoring system for use in neonates with birth weight less than 2 kg and gestational age less than 28 weeks in intensive care nursery (ICU). Seventy neonates with birth weight less than 2 kg and gestational age less than 28 weeks were divided into four groups according to their postnatal age and were examined in the ICU (1, 1-3, 3-6, and 6-14 days). Using the neonatal acute physiology score (NAPS) in the first postnatal day, the significant predictors of morbidity and mortality were identified by the logistic multiple regression analysis. The predictors of morbidity were the NAPS in the first postnatal day [odds ratio (OR), 1.49; 95% confidence interval (CI), 1.16-1.91] and the total postnatal age (OR, 1.02; 95% CI, 1.00-1.03). The predictors of mortality were the total postnatal age (OR, 1.04; 95% CI, 1.02-1.06) and the NAPS in the first postnatal day (OR, 1.07; 95% CI, 595f342e71
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